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CD46 Protein (CD46) (His tag)

CD46 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
N° du produit ABIN1098582
  • Antigène Voir toutes CD46 Protéines
    CD46
    Type de proteíne
    Recombinant
    Origine
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CD46 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Pureté
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product CD46 Protéine
  • Commentaires

    Synonyms: Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    CD46
    Autre désignation
    CD46 (CD46 Produits)
    Synonymes
    AHUS2 Protein, MCP Protein, MIC10 Protein, TLX Protein, TRA2.10 Protein, Mcp Protein, CD46 Protein, CD46 molecule Protein, CD46 antigen, complement regulatory protein Protein, CD46 molecule, complement regulatory protein Protein, membrane cofactor protein-like Protein, CD46 Protein, Cd46 Protein, LOC100341359 Protein, LOC103789310 Protein
    Sujet
    Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1–4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    33.8 kDa (302aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_758860
    Pathways
    Regulation of Actin Filament Polymerization
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