BIM Protein (His tag)
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- Antigène Voir toutes BIM (BCL2L11) Protéines
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BIM protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Pureté
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product BCL2L11 Protéine
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- Commentaires
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Synonyms: BCL2-like 11, BAM, BIM, BIM-alpha6, BIM-beta6, BIM-beta7, BimEL, BimL, BOD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer, pH 8.0, 2 M Urea, 20% glycerol 5 MM DTT, 300 mM NaCl
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Autre désignation
- BCL2L11 (BCL2L11 Produits)
- Synonymes
- bim Protein, BAM Protein, BIM Protein, BOD Protein, 1500006F24Rik Protein, Bim Protein, Bod Protein, BimL Protein, BIMEL Protein, BCL2-like 11 Protein, BCL2 like 11 Protein, BCL2-like 11 (apoptosis facilitator) Protein, bcl2l11 Protein, BCL2L11 Protein, Bcl2l11 Protein
- Sujet
- BCL2L11 (Bcl-2-like protein 11) belongs to the Bcl-2 family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The expression of BCL2L11 can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. Recombinant human BCL2L11 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Poids moléculaire
- 18.5kDa (162aa)
- NCBI Accession
- NP_006529
- Pathways
- Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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