HAND1 Protein (His tag)

N° du produit ABIN1098692

Détail du produit

Antigène: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HAND1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Heart and neural crest derivatives-expressed protein 1, bHLHa27, eHand, Hxt, Thing1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Autre désignation: HAND1 (HAND1 Produits)

Synonymes: CATG Protein, CG Protein, Hxt Protein, Thing1 Protein, bHLHa27 Protein, eHand Protein, eHAND Protein, hand-1 Protein, hand1-A Protein, HXT Protein, HAND1 Protein, hxt Protein, thing1 Protein, EHAND Protein, Hand1 Protein, Ehand1 Protein, Th1 Protein, cathepsin G Protein, heart and neural crest derivatives expressed 1 Protein, heart and neural crest derivatives expressed 1 L homeolog Protein, CTSG Protein, HAND1 Protein, Hand1 Protein, hand1.L Protein, hand1 Protein

Sujet: HAND1 belongs to the basic helix-loop-helix family of transcription factors. This protein is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. Recombinant human HAND1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 26 kDa (238aa)

NCBI Accession: NP_004812

Pathways: Tube Formation