MBL2 Protein (AA 108-248) (His tag)

N° du produit ABIN1098702

Détail du produit

Antigène: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Type de proteíne: Recombinant

Attributs du protein: AA 108-248

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MBL2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Mannose-binding protein C, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M Nacl

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Autre désignation: MBL2 (MBL2 Produits)

Synonymes: COLEC1 Protein, HSMBPC Protein, MBL Protein, MBL2D Protein, MBP Protein, MBP-C Protein, MBP1 Protein, MBPD Protein, pMBP-27 Protein, mbl2 Protein, MBL1 Protein, cMBl Protein, collectin Protein, Ab2-001 Protein, Ab2-011 Protein, L-MBP Protein, MBL-C Protein, COLEC2 Protein, mbl Protein, etID42583.2 Protein, fb68b07 Protein, hbl3 Protein, wu:fb68b07 Protein, zgc:109836 Protein, mannose binding lectin 2 Protein, Mannose-binding protein C Protein, mannose-binding lectin (protein C) 2, soluble Protein, mannose-binding lectin (protein C) 2 Protein, mannose-binding lectin family member 3, pseudogene Protein, MBL2 Protein, mbl2 Protein, Mbl2 Protein, MBL3P Protein

Sujet: Mannose-binding protein C, also known as MBL2, is a member of the collectin family of patternrecognition molecules. MBL2 is a secreted glycoprotein that is synthesized as a 248 amino acid precursor. The Protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. Recombinant human MBL2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 18 kDa (164aa)

NCBI Accession: NP_000233

UniProt: P11226

Pathways: Système du Complément, Positive Regulation of Immune Effector Process