IRGM Protein (His tag)

N° du produit ABIN1098712

Détail du produit

Antigène: IRGM (Immunity-Related GTPase Family, M (IRGM))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IRGM protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Immunity-related GTPase family M protein, IFI1, IRGM1, LRG-47, LRG47, MGC149263, MGC149264

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: IRGM (Immunity-Related GTPase Family, M (IRGM))

Autre désignation: IRGM (IRGM Produits)

Synonymes: Ifi1 Protein, Iigp3 Protein, Iipg3 Protein, Irgm Protein, LRG-47 Protein, IFI1 Protein, IRGM1 Protein, LRG47 Protein, immunity-related GTPase family M member 1 Protein, immunity-related GTPase M Protein, immunity related GTPase M Protein, immunity-related GTPase family M protein Protein, Irgm1 Protein, Irgm Protein, IRGM Protein, LOC481473 Protein

Sujet: Immunity-related GTPase family M protein, also known as IRGM, is required for clearance of acute protozoan and bacterial infections. This protein functions in innate immune response probably through regulation of autophagy. It may regulate proinflammatory cytokine production and prevent endotoxemia upon infection and may also play a role in macrophages adhesion and motility. Recombinant human IRGM protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 20.1 kDa (180aa)

NCBI Accession: NP_001139277