Inhibin alpha Protein (His tag)

N° du produit ABIN1098742

Détail du produit

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Inhibin alpha protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: inhibin alpha chain, A inhibin subunit precursor, IHA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Autre désignation: INHA (INHA Produits)

Synonymes: si:dkey-91f15.2 Protein, INHA Protein, MGC108500 Protein, AW555078 Protein, inhibin, alpha Protein, inhibin alpha subunit Protein, inhibin alpha Protein, inhibin alpha L homeolog Protein, inha Protein, INHA Protein, inha.L Protein, Inha Protein

Sujet: INHA, also known as Inhibin alpha, belongs to the TGF-beta family. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Recombinant human INHA protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 17.0kDa (155aa)

NCBI Accession: NP_002182

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion