SGCD Protein (His tag)

N° du produit ABIN1098776

Détail du produit

Antigène: SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SGCD protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Delta-sarcoglycan, 35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))

Autre désignation: SGCD (SGCD Produits)

Synonymes: BEST:GH21860 Protein, CG14808 Protein, CT34621 Protein, DmSCG-gammadelta Protein, Dmel\\CG14808 Protein, EG:4F1.1 Protein, GH21860 Protein, Sgcd Protein, wu:fc49e11 Protein, zgc:110649 Protein, 35DAG Protein, CMD1L Protein, DAGD Protein, SG-delta Protein, SGCDP Protein, SGD Protein, Delta-SG Protein, 35kDa Protein, delta-SG Protein, sarcoglycan delta Protein, Sarcoglycan delta Protein, sarcoglycan, delta (dystrophin-associated glycoprotein) Protein, sarcoglycan, delta Protein, SGCD Protein, Scgdelta Protein, sgcd Protein, Sgcd Protein

Sujet: SGCD is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. The mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed. In melanocytic cells SGCD gene expression may be regulated by MITF. Recombinant human SGCD protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 28 kDa (257aa)

NCBI Accession: NP_001121681

Pathways: Maintenance of Protein Location