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FASL Protein (AA 103-281, Extracellular Domain, Soluble) (DYKDDDDK Tag)

FASL Origine: Humain, Souris Hôte: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
N° du produit ABIN1344396
  • Antigène Voir toutes FASL Protéines
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    Soluble, Extracellular Domain, AA 103-281
    Origine
    • 19
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Source
    • 11
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette FASL protéine est marqué à la DYKDDDDK Tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    The extracellular domain of human FasL (aa 103-281) is fused at the N-terminus to a FLAG®-tag.
    Pureté
    >95 % (SDS-PAGE)
    niveau d'endotoxine
    <0.05EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product FASL Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1μg/ml TNF Ligands Enhancer (Prod. No. AG-35B-0001). In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    Autre désignation
    FasL (FASL Produits)
    Synonymes
    ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
    Sujet
    FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.
    Poids moléculaire
    ~33kDa (SDS-PAGE)
    UniProt
    P48023
    Pathways
    Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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