APEX1 Protein (AA 1-318) (GST tag)
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- Antigène Voir toutes APEX1 Protéines
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-318
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Origine
- Humain
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Source
- Wheat germ
- Purification/Conjugué
- Cette APEX1 protéine est marqué à la GST tag.
- Application
- Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
- Fonction
- APEX1 (Human) Recombinant Protein (P01)
- Séquence
- MPKRGKKGAV AEDGDELRTE PEAKKSKTAA KKNDKEAAGE GPALYEDPPD QKTSPSGKPA TLKICSWNVD GLRAWIKKKG LDWVKEEAPD ILCLQETKCS ENKLPAELQE LPGLSHQYWS APSDKEGYSG VGLLSRQCPL KVSYGIGEEE HDQEGRVIVA EFDSFVLVTA YVPNAGRGLV RLEYRQRWDE AFRKFLKGLA SRKPLVLCGD LNVAHEEIDL RNPKGNKKNA GFTPQERQGF GELLQAVPLA DSFRHLYPNT PYAYTFWTYM MNARSKNVGW RLDYFLLSHS LLPALCDSKI RSKALGSDHC PITLYLAL
- Attributs du produit
- Human APEX1 full-length ORF ( AAH02338, 1 a.a. - 318 a.a.) recombinant protein with GST-tag at N-terminal.
- Purification
- in vitro wheat germ expression system
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. - Restrictions
- For Research Use only
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Conseil sur la manipulation
- Aliquot to avoid repeated freezing and thawing.
- Stock
- -80 °C
- Stockage commentaire
- Best use within three months from the date of receipt of this protein.
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Bcl2 inhibits abasic site repair by down-regulating APE1 endonuclease activity." dans: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9925-32, (2008) (PubMed).
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Bcl2 inhibits abasic site repair by down-regulating APE1 endonuclease activity." dans: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9925-32, (2008) (PubMed).
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- Antigène
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Autre désignation
- APEX1 (APEX1 Produits)
- Synonymes
- apex1 Protein, MGC76280 Protein, MGC79645 Protein, MGC78928 Protein, APE Protein, APE1 Protein, APEN Protein, APEX Protein, APX Protein, HAP1 Protein, REF1 Protein, Apex Protein, REF-1 Protein, BAP1 Protein, apex1a Protein, hm:zehn1532 Protein, wu:fc13d11 Protein, zgc:66204 Protein, Ref-1 Protein, apurinic/apyrimidinic endodeoxyribonuclease 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog Protein, DNA-(apurinic or apyrimidinic site) lyase Protein, apurinic/apyrimidinic endonuclease 1 Protein, APEX1 Protein, apex1 Protein, apex1.L Protein, CNG03640 Protein, CNH01280 Protein, nth Protein, Spirs_4119 Protein, Palpr_0103 Protein, Apex1 Protein
- Sujet
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Full Gene Name: APEX nuclease (multifunctional DNA repair enzyme) 1
Synonyms: APE,APE-1,APE1,APEN,APEX,APX,HAP1,REF-1,REF1 - ID gène
- 328
- Pathways
- Réparation de l'ADN, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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