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CGREF1 Protein (AA 20-301) (His tag)

CGREF1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1691476
  • Antigène Tous les produits CGREF1
    CGREF1 (Cell Growth Regulator with EF-Hand Domain 1 (CGREF1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 20-301
    Origine
    • 5
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CGREF1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human CGREF1/CGR11 (C-6His)
    Séquence
    APKDGVTRPD SEVQHQLLPN PFQPGQEQLG LLQSYLKGLG RTEVQLEHLS REQVLLYLFA LHDYDQSGQL DGLELLSMLT AALAPGAANS PTTNPVILIV DKVLETQDLN GDGLMTPAEL INFPGVALRH VEPGEPLAPS PQEPQAVGRQ SLLAKSPLRQ ETQEAPGPRE EAKGQVEARR ESLDPVQEPG GQAEADGDVP GPRGEAEGQA EAKGDAPGPR GEAGGQAEAE GDAPGPRGEA GGQAEARENG EEAKELPGET LESKNTQNDF EVHIVQVEND EIVDHHHHHH
    Attributs du produit
    Recombinant Human Cell Growth Regulator with EF Hand Domain Protein 1/CGREF1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala20-Ile301) of Human CGREF1 fused with a polyhistidine tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2, pH 7.5.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    CGREF1 (Cell Growth Regulator with EF-Hand Domain 1 (CGREF1))
    Autre désignation
    CGREF1 (CGREF1 Produits)
    Synonymes
    CGR11 Protein, CGREF1 Protein, 1110004G24Rik Protein, AW045201 Protein, Cgr11 Protein, cell growth regulator with EF-hand domain 1 Protein, cell growth regulator with EF-hand domain 1 L homeolog Protein, cell growth regulator with ring finger domain 1 Protein, cell growth regulator with EF hand domain 1 Protein, CGREF1 Protein, cgref1.L Protein, cgref1 Protein, CGRRF1 Protein, Cgref1 Protein
    Sub Type
    Fusionprotein
    Sujet
    Cell Growth Regulator with EF Hand Domain Protein 1 (CGREF1) is a secreted calcium ion binding protein. CGREF1 contains two EF-hand domains and both EF-hands are required for function. Human CGREF1 is synthesized as a 301 amino acid precursor that contains a 19 amino acid signal sequence, and a 282 amino acid mature chain. CGREF1 is probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides. CGREF1 mediates cell-cell adhesion in a calcium-dependent manner. In addition, CGREF1 is able to inhibit growth in several cell lines.
    Alternative Names: Cell Growth Regulator with EF Hand Domain Protein 1, Cell Growth Regulatory Gene 11 Protein, Hydrophobestin, CGREF1, CGR11
    Poids moléculaire
    30.9 kDa
    UniProt
    Q99674
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