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CD72 Protein (AA 117-226) (His tag,TRX tag)

CD72 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1691965
  • Antigène Voir toutes CD72 Protéines
    CD72 (CD72 Molecule (CD72))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 117-226
    Origine
    • 14
    • 3
    • 2
    Humain
    Source
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CD72 protéine est marqué à la His tag,TRX tag.
    Fonction
    Recombinant Human B-Cell Differentiation Antigen CD72/Lyb-2 (N-Trx, 6His)
    Séquence
    MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ADIGSMRYLQ VSQQLQQTNR VLEVTNSSLR QQLRLKITQL GQSAEDLQGS RRELAQSQEA LQVEQRAHQA AEGQLQACQA DRQKTKETLQ SEEQQRRALE QKLSNMENRL KPFFTC
    Attributs du produit
    Recombinant Human B-Cell Differentiation Antigen CD72/CD72 is produced with our E. coli expression system. The target protein is expressed with sequence (Arg117-Cys226) of Human CD72.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD72 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    CD72 (CD72 Molecule (CD72))
    Autre désignation
    CD72 (CD72 Produits)
    Synonymes
    CD72c Protein, Ly-19 Protein, Ly-32 Protein, Ly-m19 Protein, Lyb-2 Protein, CD72b Protein, LYB2 Protein, CD72 antigen Protein, CD72 molecule Protein, Cd72 Protein, CD72 Protein
    Sujet
    B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
    Alternative Names: B-Cell Differentiation Antigen CD72, Lyb-2, CD72
    Poids moléculaire
    30.6 kDa
    UniProt
    P21854
    Pathways
    BCR Signaling
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