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CD72 Protein (TRX tag,His tag)

CD72 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318196
  • Antigène Voir toutes CD72 Protéines
    CD72 (CD72 Molecule (CD72))
    Type de proteíne
    Recombinant
    Origine
    • 14
    • 3
    • 2
    Humain
    Source
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CD72 protéine est marqué à la TRX tag,His tag.
    Fonction
    Recombinant Human CD72/Lyb-2 Protein (Trx&His)
    Séquence
    Arg117-Cys226
    Attributs du produit
    Recombinant Human B-Cell Differentiation Antigen CD72 is produced by our E.coli expression system and the target gene encoding Arg117-Cys226 is expressed with a Trx, 6His tag at the N-terminus.
    Pureté
    > 90 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD72 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    CD72 (CD72 Molecule (CD72))
    Autre désignation
    CD72/Lyb-2 (CD72 Produits)
    Synonymes
    CD72c Protein, Ly-19 Protein, Ly-32 Protein, Ly-m19 Protein, Lyb-2 Protein, CD72b Protein, LYB2 Protein, CD72 antigen Protein, CD72 molecule Protein, Cd72 Protein, CD72 Protein
    Sujet

    Background: B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.

    Synonym: B-Cell Differentiation Antigen CD72, Lyb-2, CD72

    Poids moléculaire
    30.6 kDa
    UniProt
    P21854
    Pathways
    BCR Signaling
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