UBE2V2 Protein (AA 1-145) (His tag)

N° du produit ABIN1692317

Détail du produit

Antigène: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-145

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBE2V2 protéine est marqué à la His tag.

Fonction: Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 2/UBE2V2/DDVIT1 (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MAVSTGVKVP RNFRLLEELE EGQKGVGDGT VSWGLEDDED MTLTRWTGMI IGPPRTNYEN RIYSLKVECG PKYPEAPPSV RFVTKINMNG INNSSGMVDA RSIPVLAKWQ NSYSIKVVLQ ELRRLMMSKE NMKLPQPPEG QTYNN

Attributs du produit: Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 2/UBE2V2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn145) of Human UBE2V2 fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 50mm HEPES,150 mM NaCl, pH 7.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Autre désignation: UBE2V2 (UBE2V2 Produits)

Synonymes: DDVIT1 Protein, DDVit-1 Protein, EDAF-1 Protein, EDPF-1 Protein, EDPF1 Protein, MMS2 Protein, UEV-2 Protein, UEV2 Protein, mms2 Protein, uev2 Protein, edpf1 Protein, uev-2 Protein, ddvit1 Protein, edaf-1 Protein, edpf-1 Protein, ddvit-1 Protein, 1110021H13Rik Protein, 4632410D19Rik Protein, 5730524P06Rik Protein, 6820402M05 Protein, AI848315 Protein, C81524 Protein, wu:fb18b11 Protein, wu:fb24d11 Protein, zgc:63717 Protein, UBE2V2 Protein, TMEM189-UBE2V1 Protein, ubiquitin conjugating enzyme E2 V2 Protein, ubiquitin-conjugating enzyme E2 variant 2 Protein, ubiquitin conjugating enzyme E2 V2 S homeolog Protein, Ubiquitin-conjugating enzyme E2 variant 2 Protein, UBE2V2 Protein, Ube2v2 Protein, ube2v2 Protein, ube2v2.S Protein, PTRG_00824 Protein, ub2v2 Protein, Tsp_08004 Protein

Sub Type: Fusionprotein

Sujet: Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Alternative Names: Ubiquitin-Conjugating Enzyme E2 Variant 2, DDVit 1, Enterocyte Differentiation-Associated Factor 1, EDAF-1, Enterocyte Differentiation-Promoting Factor 1, EDPF-1, MMS2 Homolog, Vitamin D3-Inducible Protein, UBE2V2, MMS2, UEV2

Poids moléculaire: 18.5 kDa

UniProt: Q15819

Pathways: Positive Regulation of Response to DNA Damage Stimulus