UBE2V2 Protein (AA 2-145) (His-SUMO Tag)
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- UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 2-145
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette UBE2V2 protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- AVSTGVKVPR NFRLLEELEE GQKGVGDGTV SWGLEDDEDM TLTRWTGMII GPPRTNYENR IYSLKVECGP KYPEAPPSVR FVTKINMNGI NNSSGMVDAR SIPVLAKWQN SYSIKVVLQE LRRLMMSKEN MKLPQPPEGQ TYNN
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product UBE2V2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))
- Autre désignation
- UB2V2 (UBE2V2 Produits)
- Synonymes
- DDVIT1 Protein, DDVit-1 Protein, EDAF-1 Protein, EDPF-1 Protein, EDPF1 Protein, MMS2 Protein, UEV-2 Protein, UEV2 Protein, mms2 Protein, uev2 Protein, edpf1 Protein, uev-2 Protein, ddvit1 Protein, edaf-1 Protein, edpf-1 Protein, ddvit-1 Protein, 1110021H13Rik Protein, 4632410D19Rik Protein, 5730524P06Rik Protein, 6820402M05 Protein, AI848315 Protein, C81524 Protein, wu:fb18b11 Protein, wu:fb24d11 Protein, zgc:63717 Protein, UBE2V2 Protein, TMEM189-UBE2V1 Protein, ubiquitin conjugating enzyme E2 V2 Protein, ubiquitin-conjugating enzyme E2 variant 2 Protein, ubiquitin conjugating enzyme E2 V2 S homeolog Protein, Ubiquitin-conjugating enzyme E2 variant 2 Protein, UBE2V2 Protein, Ube2v2 Protein, ube2v2 Protein, ube2v2.S Protein, PTRG_00824 Protein, ub2v2 Protein, Tsp_08004 Protein
- Sujet
- Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
- Poids moléculaire
- 32.2 kDa
- UniProt
- Q15819
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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