Cyclin T1 Protein (CCNT1) (AA 1-726) (GST tag)

N° du produit ABIN1989589

Détail du produit

Antigène: Cyclin T1 (CCNT1)

Type de proteíne: Recombinant

Attributs du protein: AA 1-726

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette Cyclin T1 protéine est marqué à la GST tag.

Application: ELISA, Western Blotting (WB), Antibody Array (AA), Affinity Purification (AP)

Fonction: CCNT1 (Human) Recombinant Protein (P01)

Séquence: MEGERKNNNK RWYFTREQLE NSPSRRFGVD PDKELSYRQQ AANLLQDMGQ RLNVSQLTIN TAIVYMHRFY MIQSFTQFPG NSVAPAALFL AAKVEEQPKK LEHVIKVAHT CLHPQESLPD TRSEAYLQQV QDLVILESII LQTLGFELTI DHPHTHVVKC TQLVRASKDL AQTSYFMATN SLHLTTFSLQ YTPPVVACVC IHLACKWSNW EIPVSTDGKH WWEYVDATVT LELLDELTHE FLQILEKTPN GLKRIWNWRA CEAAKKTKAD DRGTDEKTSE QTILNMISQS SSDTTIAGLM SMSTSTTSAV PSLPVSEESS SNLTSVEMLP GKRWLSSQPS FKLEPTQGHR TSENLALTGV DHSLPQDGSN AFISQKQNSK SVPSAKVSLK EYRAKHAEEL AAQKRQLENM EANVKSQYAY AAQNLLSHHD SHSSVILKMP IEGSENPERP FLEKADKTAL KMRIPVAGGD KAASSKPEEI KMRIKVHAAA DKHNSVEDSV TKSREHKEKH KTHPSNHHHH HNHHSHKHSH SQLPVGTGNK RPGDPKHSSQ TSNLAHKTYS LSSSFSSSSS TRKRGPSEET GGAVFDHPAK IAKSTKSSSL NFSFPSLPTM GQMPGHSSDT SGLSFSQPSC KTRVPHSKLD KGPTGANGHN TTQTIDYQDT VNMLHSLLSA QGVQPTQPTA FEFVRPYSDY LNPRSGGISS RSGNTDKPRP PPLPSEPPPP LPPLPK

Attributs du produit: Human CCNT1 full-length ORF (BAF83679.1, 1 a.a. - 726 a.a.) recombinant protein with GST tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Détail du antigène

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1 (CCNT1 Produits)

Synonymes: CG6292 Protein, Dmcyclin T Protein, Dmel\\CG6292 Protein, ORE-14 Protein, P-TEFb Protein, anon-74EFc Protein, dT Protein, p124 Protein, Cyclin-T1 Protein, ccnt Protein, cyct1 Protein, CCNT Protein, CYCT1 Protein, HIVE1 Protein, 2810478G24Rik Protein, AI115585 Protein, CycT1 Protein, fi75b02 Protein, si:dkey-18f23.10 Protein, wu:fi75b02 Protein, Cyclin T Protein, cyclin T1 Protein, cyclin T1 L homeolog Protein, CycT Protein, CCNT1 Protein, ccnt1 Protein, Ccnt1 Protein, ccnt1.L Protein

Sujet: Synonyms: CCNT,CYCT1
Gene Description: cyclin T1
Gene Name: CCNT1
Gene Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.
GenBank: AK290990.1, BAF83679.1

Poids moléculaire: 107 kDa (theoreatical)

ID gène: 904