IFNB1 Protein (AA 22-187)
Aperçu rapide pour IFNB1 Protein (AA 22-187) (ABIN2017995)
Antigène
Voir toutes IFNB1 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 22-187
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Attributs du produit
- ED50 < 0.1 ng/mL, measured in a proliferation assay using TF-1 Cells.
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niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Stock
- -80 °C
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Stockage commentaire
- Lyophilized recombinant Human Interferon-beta remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interferon-beta should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Date de péremption
- 6 months
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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Autre désignation
- Interferon-beta
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Sujet
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Interferon-beta (IFN-beta), acting via STAT1 and STAT2, is known to upregulate and downregulate a wide variety of genes, most of which are involved in the antiviral immune response. It is a member of Type I IFNs, which include IFN-alpha, -beta, tau, and omega. IFN-beta plays an important role in inducing non-specific resistance against a broad range of viral infections. It also affects cell proliferation and modulates immune responses.
Synonyms: Leukocyte interferon, B cell interferon, Type I interferon -
Poids moléculaire
- 23 kDa, observed by reducing SDS-PAGE.
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UniProt
- P01574
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Pathways
- Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
Antigène
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