IL-11 Protein (AA 22-199)
Aperçu rapide pour IL-11 Protein (AA 22-199) (ABIN7477977)
Antigène
Voir toutes IL-11 (IL11) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 22-199
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Attributs du produit
- ED50 <5 ng/mL, measured in a proliferation assay using T11 cells.
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niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 11 (IL11) (AA 22-199) protein (His tag)
IL11 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Origine: Humain Hôte: Escherichia coli (E. coli) > 90 % CC, AcA Active
Interleukin 11 (IL11) (Active) proteinIL11 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 11 (IL11) protein (Fc Tag)IL11 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 11 (IL11) (AA 1-199) protein (GST tag)IL11 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 11 (IL11) proteinIL11 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Stock
- -80 °C
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Stockage commentaire
- Lyophilized recombinant Human Interleukin-11 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Interleukin-11 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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Date de péremption
- 6 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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Autre désignation
- Interleukin-11
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Sujet
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Interleukin-11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 has multiple effects on both hematopoietic and non-hematopoietic cells. Many of the biological effects described for IL-11 overlap with those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell-dependent development of specific immunoglobulin-secreting B cells.
Synonyms: AGIF (Adipogenesis inhibitory factor) -
Poids moléculaire
- 23 kDa, observed by reducing SDS-PAGE.
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UniProt
- P20809
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Pathways
- Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
Antigène
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