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TWEAK Protein (AA 99-249)

TNFSF12 Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
N° du produit ABIN2018425
  • Antigène Voir toutes TWEAK (TNFSF12) Protéines
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 99-249
    Origine
    • 16
    • 5
    • 2
    Humain
    Source
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    CHO Cells
    Attributs du produit
    ED50 < 1 ng/mL, measured in a cell cytotoxicity assay using HTB-38 (HT-29) cells.
    Pureté
    > 95 % as analyzed by SDS-PAGE and HPLC.
    niveau d'endotoxine
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product TNFSF12 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Stock
    -80 °C
    Stockage commentaire
    Lyophilized recombinant Human TWEAK remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TWEAK should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Date de péremption
    6 months
  • Antigène
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Autre désignation
    TWEAK (TNFSF12 Produits)
    Synonymes
    APO3L Protein, DR3LG Protein, TWEAK Protein, Apo3l Protein, Dr3l Protein, Dr3lg Protein, Tweak Protein, TNF superfamily member 12 Protein, tumor necrosis factor (ligand) superfamily, member 12 Protein, TNFSF12 Protein, Tnfsf12 Protein
    Sujet
    TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-kappaB activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.
    Synonyms: TNF-related weak inducer of apoptosis, TNFSF12, DR3LG, Apo3-Ligand
    Poids moléculaire
    20-22 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q4ACW9
    Pathways
    Apoptose
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