EGF Protéine
Aperçu rapide pour EGF Protéine (ABIN2129047)
Antigène
Voir toutes EGF ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
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Attributs du produit
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Purified recombinant Mouse EGF protein
Expression System: E.coli
Bioactivity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is 1 x 10^7 units/mg. -
niveau d'endotoxine
- < 0.1 ng per μg (1 EU/μg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Commentaires
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Biological activity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is 1 x 10^7 units/mg.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 10 mM Na3PO4, pH 7.5.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- EGF (Epidermal Growth Factor (EGF))
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Autre désignation
- EGF
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Sujet
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Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF alpha and VGF (vaccinia virus growth factor).
Alternative Names: Epidermal Growth Factor protein, URG protein, Urogastrone protein -
Poids moléculaire
- 6.0 kDa
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Antigène
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