ANGPTL4 Protein (AA 166-406) (His tag)
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- Antigène Voir toutes ANGPTL4 Protéines
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 166-406
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ANGPTL4 protéine est marqué à la His tag.
- Séquence
- AA 166-406
- Attributs du produit
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 33-36 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Pureté
- >95 % as determined by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ANGPTL4 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM MOPS, 100 mM NaCl, pH 7.2
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Antigène
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- Autre désignation
- Angiopoietin-Like 4 (ANGPTL4 Produits)
- Synonymes
- ANGPTL2 Protein, ARP4 Protein, FIAF Protein, HFARP Protein, NL2 Protein, PGAR Protein, pp1158 Protein, Arp4 Protein, Bk89 Protein, Fiaf Protein, Hfarp Protein, Ng27 Protein, Pgar Protein, Pgarg Protein, Pp1158 Protein, ANGPTL4 Protein, fiaf Protein, im:7144703 Protein, si:rp71-39b20.7 Protein, angiopoietin like 4 Protein, angiopoietin-like 4 Protein, ANGPTL4 Protein, Angptl4 Protein, angptl4 Protein
- Sujet
- Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
- Poids moléculaire
- 27.9 kDa
- NCBI Accession
- NP_647475
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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