MBP/MBL Protein (AA 21-248) (His tag)

N° du produit ABIN2181498

Détail du produit

Antigène: MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))

Type de proteíne: Recombinant

Attributs du protein: AA 21-248

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MBP/MBL protéine est marqué à la His tag.

Séquence: AA 21-248

Attributs du produit: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.8 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE).

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Détail du antigène

Antigène: MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))

Autre désignation: MBL (MBP/MBL Produits)

Synonymes: COLEC1 Protein, HSMBPC Protein, MBL Protein, MBL2D Protein, MBP Protein, MBP-C Protein, MBP1 Protein, MBPD Protein, pMBP-27 Protein, MBL1 Protein, cMBl Protein, collectin Protein, L-MBP Protein, MBL-C Protein, RaRF p28A Protein, mbl Protein, mannose binding lectin 2 Protein, mannose-binding lectin (protein C) 2 Protein, mannose-binding protein C-like Protein, MBL2 Protein, Mbl2 Protein, LOC100911854 Protein

Sujet: Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

Poids moléculaire: 25.9 kDa