TTR Protein (AA 21-147) (His tag)

N° du produit ABIN2181876

Détail du produit

Antigène: TTR (Transthyretin (TTR))

Type de proteíne: Recombinant

Attributs du protein: AA 21-147

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TTR protéine est marqué à la His tag.

Séquence: AA 21-147

Attributs du produit: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.6 kDa. The protein migrates as 19 kDa and 37 kDa under reducing (R) condition (SDS-PAGE) due to the monomer and dimer respectively.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Détail du antigène

Antigène: TTR (Transthyretin (TTR))

Autre désignation: Transthyretin (TTR Produits)

Synonymes: zgc:103583 Protein, TTR Protein, LOC100226992 Protein, CTS Protein, CTS1 Protein, HsT2651 Protein, PALB Protein, TBPA Protein, AA408768 Protein, AI787086 Protein, D17860 Protein, prealbumin Protein, Lr1 Protein, Tbpa Protein, Prealbumin Protein, xTTR Protein, transthyretin (prealbumin, amyloidosis type I) Protein, transthyretin Protein, Transthyretin Protein, transthyretin (prealbumin, amyloidosis type 1) Protein, transthyretin-like Protein, transthyretin L homeolog Protein, ttr Protein, TTR Protein, vpb38 Protein, MRAD2831_RS38185 Protein, Caci_4246 Protein, LOC100226992 Protein, Ttr Protein, ttr.L Protein

Sujet: Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family. Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1 % of TTR's T4 binding sites are occupied in blood. TTR misfolding and aggregation is known to be associated with the amyloid diseases.

Poids moléculaire: 14.9 kDa

NCBI Accession: NP_000362

Pathways: Hormone Transport