CD4 Protein (CD4) (His tag)

N° du produit ABIN2566413

Cette protéine Recombinant CD4 est produite dans HEK-293 Cells.

Aperçu rapide pour CD4 Protein (CD4) (His tag) (ABIN2566413)

Antigène: CD4

Type de proteíne: Recombinant

Origine: Cynomolgus

Source: HEK-293 Cells

Application: Western Blotting (WB)

Pureté: >95 % as determined by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette CD4 protéine est marqué à la His tag.

Information d'application

Indications d'application: This recombinant protein can be used for WB. For research use only.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -80 °C,-20 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: CD4

Autre désignation: CD4

Sujet: T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Poids moléculaire: 42.3 kDa

UniProt: G7N5T8

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events