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PIGR Protein (His tag)

PIGR Origine: Humain Hôte: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. WB, ELISA Active
N° du produit ABIN2566874
  • Antigène Voir toutes PIGR Protéines
    PIGR (Polymeric Immunoglobulin Receptor (PIGR))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 16
    • 8
    • 4
    • 4
    • 1
    Humain
    Source
    • 15
    • 6
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PIGR protéine est marqué à la His tag.
    Application
    Western Blotting (WB), ELISA
    Attributs du produit

    Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human PIGR at 2 μg/mL, the concentration of human IgM that produces 50 % of the optimal binding response is appoximately 20-200 ng/mL.

    Pureté
    >98 % as determined by SDS-PAGE.
    Top Product
    Discover our top product PIGR Protéine
  • Indications d'application
    This recombinant protein can be used for WB, ELISA. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -80 °C,-20 °C
    Stockage commentaire
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Antigène
    PIGR (Polymeric Immunoglobulin Receptor (PIGR))
    Autre désignation
    Poly Ig Receptor (PIGR Produits)
    Synonymes
    DKFZp469G1013 Protein, RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein
    Sujet
    Polymeric immunoglobulin receptor (PIGR) is also known as Poly-Ig receptor, which can be cleaved into membrane secretory component (SC). PIGR is a type I transmembrane glycoprotein or a member of the immunoglobulin superfamily, and is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
    Poids moléculaire
    68.7 kDa
    ID gène
    5284
    UniProt
    P01833
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