PPARD Protein (His tag)

N° du produit ABIN2669421

Détail du produit

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PPARD protéine est marqué à la His tag.

Application: Protein Interaction (PI)

Attributs du produit: Recombinant PPARβ(δ) is isolated from an E. coli strain that carries the coding sequence of the human PPARβ(δ) under the control of a T7 promoter (accession number NM 006238). The purified recombinant protein has an amino terminal polyhistidine tag and is greater than 95 % homogeneous and contains no detectable protease, DNase and RNase activity.

Pureté: The purified recombinant protein has an amino terminal polyhistidine tag and is greater than 95 % homogeneous and contains no detectable protease, DNase and RNase activity.

Information d'application

Indications d'application: Recombinant PPARβ(δ) is suitable for DNA and protein-protein interaction assays. 20 ng is sufficient for gelshift assays and 100 ng is sufficient for protein-protein interaction studies. The molecular weight of the protein is ~52 kDa. NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Détail du antigène

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Autre désignation: PPARbeta (PPARD Produits)

Synonymes: FAAR Protein, NR1C2 Protein, NUC1 Protein, NUCI Protein, NUCII Protein, PPARB Protein, NUC-1 Protein, Nr1c2 Protein, PPAR-beta Protein, PPAR-delta Protein, PPAR[b] Protein, PPARdelta Protein, Pparb Protein, Pparb/d Protein, PPARBETA Protein, ppard Protein, pparb Protein, PPARD Protein, PPAR-D/B Protein, peroxisome proliferator activated receptor delta Protein, peroxisome proliferator activator receptor delta Protein, peroxisome proliferator activated receptor delta S homeolog Protein, peroxisome proliferator-activated receptor delta Protein, PPARD Protein, Ppard Protein, ppard.S Protein, ppard Protein

Sujet: Peroxisome Proliferator-Activated Receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: α, δ and Y. PPARs bind to peroxisome proliferator response elements (PPREs) as heterodimers with the retinoid X receptor (RXR).

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation