BPTF Protein (AA 2791-2911) (His tag,DYKDDDDK Tag)

N° du produit ABIN2669695

Détail du produit

Antigène: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Type de proteíne: Recombinant

Attributs du protein: AA 2791-2911

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BPTF protéine est marqué à la His tag,DYKDDDDK Tag.

Application: Binding Studies (Bind), Screening Assay (ScA)

Attributs du produit: The peptide corresponding to amino acids 2791-2911 that contains the bromodomain sequences of BPTF / FALZ (accession number NP_872579.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.3 kDa.

Information d'application

Indications d'application: Recombinant BPTF / FALZ (2791-2911) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.

Détail du antigène

Antigène: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Autre désignation: BPTF / FALZ (BPTF Produits)

Synonymes: FAC1 Protein, FALZ Protein, NURF301 Protein, 9430093H17Rik Protein, Falz Protein, BPTF Protein, bromodomain PHD finger transcription factor Protein, nucleosome-remodeling factor subunit NURF301 Protein, fetal alzheimer antigen, falz Protein, BPTF Protein, Bptf Protein, LOC5576547 Protein, CpipJ_CPIJ011285 Protein, bptf Protein

Sujet: Bromodomain PHD finger transcription factor (BPTF), also known as Fetal Alzheimer antigen (FALZ), is a histone-binding component of NuRF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. BPTF protein contains a DNA-binding domain, a zinc finger motif and a bromodomain. Bromodomains recognize acetylated histone lysine residues and function as 'readers' of these epigenetic histone marks to regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. BPTF also specifically recognizes H3 tails trimethylated on lysine 4 (H3K4me3), which mark transcription start sites of virtually all active genes. It may also regulate transcription through direct binding to DNA or transcription factors.

Poids moléculaire: 20.3 kDa