Coronin 7 Protein (CORO7) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712510

Détail du produit

Antigène: Coronin 7 (CORO7)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Coronin 7 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Coronin-7 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Coronin 7 (CORO7)

Abstract: CORO7 Produits

Synonymes: coronin-7 Protein, zgc:112352 Protein, MGC99303 Protein, Coronin-7 Protein, DKFZp459E084 Protein, 0610011B16Rik Protein, CRN7 Protein, POD1 Protein, AW048373 Protein, AW556392 Protein, Crn7 Protein, coronin 7 Protein, coronin 7 S homeolog Protein, coronin-7 Protein, CORO7 Protein, coro7 Protein, coro7.S Protein, LOC100477739 Protein, Coro7 Protein

Sujet: This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants some of which form read-through transcripts with a neighboring gene.

Poids moléculaire: 100.4 kDa

NCBI Accession: NP_078811