CYP1A2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2712754

Détail du produit

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CYP1A2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CYP1A2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Autre désignation: Cyp1a2 (CYP1A2 Produits)

Synonymes: CP12 Protein, P3-450 Protein, P450(PA) Protein, CYP1A2 Protein, CYPIA2 Protein, P450-PM4 Protein, Cyp1a1 Protein, P450-3 Protein, CYPD45 Protein, P-450d Protein, RATCYPD45 Protein, CYP1A5 Protein, CP450 Protein, CYP-IA2 Protein, cytochrome P450 family 1 subfamily A member 2 Protein, cytochrome P450 1A2 Protein, cytochrome P450 LM4 Protein, cytochrome P450, family 1, subfamily A, polypeptide 2 Protein, cytochrome P450, family 1, subfamily a, polypeptide 2 Protein, cytochrome P450 1A2-like Protein, CYP1A2 Protein, LOC100328937 Protein, Cyp1a2 Protein, VDBG_06455 Protein, LOC101825565 Protein, LOC102130662 Protein

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Poids moléculaire: 58.2 kDa

NCBI Accession: NP_000752