CPN1 Protein (His tag)

N° du produit ABIN2713157

Détail du produit

Antigène: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CPN1 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Carboxypeptidase N catalytic chain (full length, N-term HIS tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Autre désignation: Carboxypeptidase N Catalytic Chain (CPN1 Produits)

Synonymes: CPN Protein, SCPN Protein, Cpn Protein, cb1037 Protein, fa99g08 Protein, wu:fa99g08 Protein, zgc:77485 Protein, cpn Protein, scpn Protein, 0610011F20Rik Protein, carboxypeptidase N subunit 1 Protein, carboxypeptidase N, polypeptide 1 Protein, carboxypeptidase N subunit 1 S homeolog Protein, CPN1 Protein, Cpn1 Protein, cpn1 Protein, cpn1.S Protein

Sujet: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.

Poids moléculaire: 50 kDa

NCBI Accession: NP_001299

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process