CEBPA Protein (His tag)

N° du produit ABIN2713896

Détail du produit

Antigène: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CEBPA protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CEBPA (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Autre désignation: Cebpa (CEBPA Produits)

Synonymes: C/EBP-alpha Protein, CEBP Protein, C/ebpalpha Protein, CBF-A Protein, Cebp Protein, DBPCEP Protein, c/ebpa Protein, cb1062 Protein, wu:fj20f03 Protein, C/EBP Protein, C/EBPalpha Protein, xC/EBP Protein, cC/EBP Protein, C/EBP alpha Protein, CCAAT/enhancer binding protein alpha Protein, CCAAT/enhancer binding protein (C/EBP), alpha Protein, CCAAT/enhancer binding protein alpha L homeolog Protein, CEBPA Protein, Cebpa Protein, cebpa Protein, cebpa.L Protein

Sujet: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Poids moléculaire: 37.4 kDa

NCBI Accession: NP_004355

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation