ADAMTS4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714387

Détail du produit

Antigène: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ADAMTS4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ADAMTS4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Autre désignation: Adamts4 (ADAMTS4 Produits)

Synonymes: 3830423K05 Protein, ADAM-TS4 Protein, ADAMTS-2 Protein, ADMP-1 Protein, mKIAA0688 Protein, ADAMTS-4 Protein, ADAMTS4 Protein, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 Protein, ADAM metallopeptidase with thrombospondin type 1 motif 4 Protein, ADAM metallopeptidase with thrombospondin type 1 motif, 4 Protein, Adamts4 Protein, ADAMTS4 Protein

Sujet: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 90 kDa

NCBI Accession: NP_005090