AIRE Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714490

Détail du produit

Antigène: AIRE (Autoimmune Regulator (AIRE))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette AIRE protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AIRE / APECED (transcript variant AIRE-1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: AIRE (Autoimmune Regulator (AIRE))

Autre désignation: Aire,apeced (AIRE Produits)

Synonymes: AIRE1 Protein, APECED Protein, APS1 Protein, APSI Protein, PGA1 Protein, autoimmune regulator Protein, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) Protein, AaeL_AAEL013794 Protein, CpipJ_CPIJ001208 Protein, CpipJ_CPIJ001209 Protein, AIRE Protein, Aire Protein

Sujet: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Poids moléculaire: 57.5 kDa

NCBI Accession: NP_000374

Pathways: Chromatin Binding