ALIX Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714567

Détail du produit

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ALIX protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ALIX / PDCD6IP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Autre désignation: Alix,pdcd6ip (PDCD6IP Produits)

Synonymes: DDBDRAFT_0167145 Protein, DDBDRAFT_0185177 Protein, DDB_0167145 Protein, DDB_0185177 Protein, AIP1 Protein, ALIX Protein, DRIP4 Protein, HP95 Protein, AI480591 Protein, AW544830 Protein, Aip1 Protein, Alix Protein, C76364 Protein, Eig2 Protein, mKIAA1375 Protein, CG12876 Protein, DAIP1 Protein, Dmel\\CG12876 Protein, GB11744 Protein, RGD1561176 Protein, zgc:63638 Protein, wu:fb70d03 Protein, wu:fy65h02 Protein, PDCD6IP Protein, aip1 Protein, alix Protein, hp95 Protein, drip4 Protein, ALG-2 interacting protein X Protein, programmed cell death 6 interacting protein Protein, programmed cell death 6-interacting protein Protein, Programmed cell death 6 interacting protein Protein, programmed cell death 6 interacting protein L homeolog Protein, alxA Protein, PDCD6IP Protein, Pdcd6ip Protein, ALiX Protein, LOC412662 Protein, pdcd6ip Protein, Bm1_48390 Protein, pdcd6ip.L Protein

Sujet: This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.

Poids moléculaire: 95.8 kDa

NCBI Accession: NP_037506

Pathways: Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation