TUBA1A Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714588

Détail du produit

Antigène: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TUBA1A protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human alpha Tubulin / TUBA1A / TUBA3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Autre désignation: alpha Tubulin,tuba1a,tuba3 (Tuba1a Produits)

Synonymes: Tuba1 Protein, B-ALPHA-1 Protein, LIS3 Protein, TUBA3 Protein, Tuba-1 Protein, TUBA3D Protein, TUBA3E Protein, wu:fb37a10 Protein, 1t Protein, ALPHA 84C Protein, Alpha-Tubulin84B Protein, BEST:LD32507 Protein, CG1913 Protein, DM1alpha Protein, DTA1 Protein, Dmel\CG1913 Protein, T Protein, TBA1_DROME Protein, Talpha1 Protein, Tub Protein, Tub 84B Protein, Tub1C Protein, Tuba84B Protein, Tubalpha1 Protein, a-tub84B Protein, a1t Protein, aTub84B Protein, alpha-Tub Protein, alpha-Tub84B Protein, alpha-tub Protein, alpha-tub84B Protein, alpha-tubulin Protein, alpha-tubulin 84B Protein, alpha1 Protein, alpha1t Protein, alpha1tub Protein, alpha1tub84B Protein, alpha84B Protein, alphaT Protein, alphaTUB Protein, alphaTUB84B Protein, alphaTub Protein, alphaTub1 Protein, alphaTub84 Protein, alphat-1 Protein, alphatub Protein, alphatub84B Protein, anon-EST:Liang-1.59 Protein, anon-EST:Liang-2.30 Protein, chr3R:2914276..2914416 Protein, clone 1.59 Protein, clone 2.30 Protein, l(3)84Bd Protein, l(3)g3 Protein, ms(3)nc33 Protein, nc33 Protein, tub Protein, tubA84B Protein, tubalpha1 Protein, tubulin Protein, TUBA1A Protein, Tuba1a Protein, Tuba2 Protein, alphatub84 Protein, b-alpha-1 Protein, lis3 Protein, tuba1a Protein, tuba1a-a Protein, tuba1a-b Protein, tuba3 Protein, tubulin, alpha 1A Protein, tubulin alpha 1a Protein, tubulin, alpha 1a Protein, tubulin alpha-1B chain Protein, tubulin alpha-1A chain Protein, tubulin alpha-3 chain-like Protein, alpha-Tubulin at 84B Protein, tubulin alpha 1a L homeolog Protein, Tuba1a Protein, TUBA1A Protein, LOC608147 Protein, LOC100392817 Protein, LOC425049 Protein, tuba1a Protein, alphaTub84B Protein, LOC100051840 Protein, LOC100340483 Protein, LOC100726777 Protein, tuba1a.L Protein

Sujet: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 50 kDa

NCBI Accession: NP_006000

Pathways: Dynamique des Microtubules, M Phase