Bestrophin 3 Protein (BEST3) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715225

Détail du produit

Antigène: Bestrophin 3 (BEST3)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Bestrophin 3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Bestrophin-3 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Bestrophin 3 (BEST3)

Autre désignation: Bestrophin-3 (BEST3 Produits)

Synonymes: CG12327 Protein, Dmel\\CG12327 Protein, dbest3 Protein, best-3 Protein, BEST3 Protein, VMD2L3 Protein, Vmd2l3 Protein, mBest4 Protein, bestrophin-3 Protein, bestrophin 3 Protein, Bestrophin 3 Protein, BEST3 Protein, Best3 Protein, best3 Protein

Sujet: BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738] Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008].

Poids moléculaire: 50.8 kDa

NCBI Accession: NP_689652