BMX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715316

Détail du produit

Antigène: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BMX protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human BMX (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Biological Activity Comment: BMX activity verified in a biochemical assay:,BMX activity verified in a biochemical assay:

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: > 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Autre désignation: Bmx (BMX Produits)

Synonymes: BMX Protein, ETK Protein, PSCTK2 Protein, PSCTK3 Protein, Etk Protein, Etk/Bmx Protein, Tyro8 Protein, RGD1565643 Protein, BMX non-receptor tyrosine kinase Protein, BMX Protein, bmx Protein, Bmx Protein

Sujet: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 77.8 kDa

NCBI Accession: NP_001712