DUSP5 Protein (His tag)

N° du produit ABIN2719839

Détail du produit

Antigène: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette DUSP5 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DUSP5 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Autre désignation: Dusp5 (DUSP5 Produits)

Synonymes: DUSP5 Protein, wu:fc03b11 Protein, wu:fc86e02 Protein, MGC84792 Protein, dusp Protein, hvh3 Protein, DUSP Protein, HVH3 Protein, Cpg21 Protein, Gm337 Protein, dual specificity phosphatase 5 Protein, dual specificity phosphatase 5 S homeolog Protein, DUSP5 Protein, dusp5 Protein, dusp5.S Protein, Dusp5 Protein

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Poids moléculaire: 41.9 kDa

NCBI Accession: NP_004410