DYNLT1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2719883

Détail du produit

Antigène: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DYNLT1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DYNLT1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Autre désignation: Dynlt1 (DYNLT1 Produits)

Synonymes: cw-1 Protein, tctel1 Protein, dynlt1a Protein, tctex-1 Protein, MGC85297 Protein, tctex1 Protein, Ci-LC3 Protein, CW-1 Protein, TCTEL1 Protein, AGS2 Protein, Tctex1 Protein, dynein light chain Tctex-type 1 L homeolog Protein, dynein light chain Tctex-type 1 Protein, dynein, light chain, Tctex-type 1 Protein, dynlt1.L Protein, DYNLT1 Protein, dynlt1 Protein, Dynlt1 Protein

Sujet: This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 12.3 kDa

NCBI Accession: NP_006510

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling