Dysferlin Protein (DYSF) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719887

Détail du produit

Antigène: Dysferlin (DYSF)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Dysferlin protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Dysferlin (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Dysferlin (DYSF)

Autre désignation: Dysferlin (DYSF Produits)

Synonymes: DYSF Protein, fb73b05 Protein, wu:fb73b05 Protein, si:rp71-50c18.1 Protein, DKFZp459E1226 Protein, 2310004N10Rik Protein, AI604795 Protein, D6Pas3 Protein, mFLJ00175 Protein, FER1L1 Protein, LGMD2B Protein, MMD1 Protein, dysferlin Protein, dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) Protein, myoferlin Protein, DYSF Protein, dysf Protein, LOC589501 Protein, Dysf Protein

Sujet: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 241.2 kDa

NCBI Accession: NP_001124459