FGF12 Protein (Transcript Variant 2) (His tag)

N° du produit ABIN2721057

Détail du produit

Antigène: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FGF12 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human FGF12 (transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, 5 mM EDTA, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Autre désignation: Fgf12 (FGF12 Produits)

Synonymes: FHF1 Protein, FHF-1 Protein, MGC84150 Protein, FGF12 Protein, fgf12 Protein, zgc:153104 Protein, fhf1 Protein, fgf12b Protein, DKFZp459P139 Protein, FGF12B Protein, AV114868 Protein, FGF-12 Protein, Fhf1 Protein, Fhf1b Protein, fibroblast growth factor 12 Protein, fibroblast growth factor 12 S homeolog Protein, fibroblast growth factor 12a Protein, FGF12 Protein, fgf12.S Protein, fgf12a Protein, fgf12 Protein, Fgf12 Protein

Sujet: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 20.5 kDa

NCBI Accession: NP_004104

Pathways: Negative Regulation of Transporter Activity