FYN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Aperçu rapide pour FYN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721482)
Antigène
Voir toutes FYN ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- Transcript Variant 1
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Purification/Conjugué
- Cette FYN protéine est marqué à la Myc-DYKDDDDK Tag.
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Specificité
- Optimal preservation of protein structure, post-translational modifications and functions.
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Attributs du produit
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- Recombinant human FYN (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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Biological Activity Comment
- FYN activity verified in a biochemical assay:,FYN activity verified in a biochemical assay:,FYN activity verified in a biochemical assay:
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- > 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))
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Autre désignation
- Fyn
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Sujet
- This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
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Poids moléculaire
- 60.6 kDa
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NCBI Accession
- NP_002028
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Pathways
- Signalistation JAK/STAT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling
Antigène
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