GRB10 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

N° du produit ABIN2722225

Détail du produit

Antigène: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 4

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GRB10 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GRB10 / GRBIR (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Autre désignation: Grb10,grbir (GRB10 Produits)

Synonymes: grb10 Protein, zgc:91987 Protein, GRB10 Protein, grb-10 Protein, grb-ir Protein, irbp Protein, meg1 Protein, rss Protein, LOC100224775 Protein, 5730571D09Rik Protein, AI325020 Protein, Meg1 Protein, mKIAA0207 Protein, RGD1566234 Protein, GRB-IR Protein, Grb-10 Protein, IRBP Protein, MEG1 Protein, RSS Protein, growth factor receptor bound protein 10 Protein, growth factor receptor-bound protein 10a Protein, growth factor receptor bound protein 10 L homeolog Protein, growth factor receptor-bound protein 10 Protein, GRB10 Protein, grb10a Protein, grb10 Protein, grb10.L Protein, LOC100434903 Protein, Grb10 Protein

Sujet: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 60.7 kDa

NCBI Accession: NP_001001555

Pathways: Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2