HCK Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2722464

Détail du produit

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette HCK protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human HCK protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: Hck (HCK Produits)

Synonymes: laloo Protein, HCK Protein, MGC107870 Protein, JTK9 Protein, p59Hck Protein, p61Hck Protein, AI849071 Protein, Bmk Protein, Hctk Protein, p56Hck Protein, HCK proto-oncogene, Src family tyrosine kinase L homeolog Protein, HCK proto-oncogene, Src family tyrosine kinase Protein, hemopoietic cell kinase Protein, hck.L Protein, HCK Protein, hck Protein, Hck Protein

Sujet: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Poids moléculaire: 59.4 kDa

NCBI Accession: NP_002101

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling