ING1 Protein (His tag)

N° du produit ABIN2723441

Détail du produit

Antigène: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ING1 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ING1 (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Autre désignation: Ing1 (ING1 Produits)

Synonymes: p24ING1c Protein, p33 Protein, p33ING1 Protein, p33ING1b Protein, p47 Protein, p47ING1a Protein, p33ING1c Protein, zgc:136918 Protein, ING1 Protein, 2610028J21Rik Protein, AA407184 Protein, AI875420 Protein, mING1h Protein, p33Ing1 Protein, p37Ing1b Protein, xing1 Protein, inhibitor of growth family member 1 Protein, inhibitor of growth family, member 1 Protein, inhibitor of growth family member 1 S homeolog Protein, ING1 Protein, Ing1 Protein, ing1 Protein, ing1.S Protein

Sujet: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 23.5 kDa

NCBI Accession: NP_937861

Pathways: Protein targeting to Nucleus, Autophagy