JAM3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723925

Détail du produit

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette JAM3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human JAM3 / JAM-C protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Autre désignation: Jam3,jam-C (JAM3 Produits)

Synonymes: JAM3 Protein, jam3 Protein, sr:nyz155 Protein, wu:fb30h11 Protein, wu:fc08c06 Protein, wu:fc13e04 Protein, wu:fc25g11 Protein, jamc.2 Protein, 1110002N23Rik Protein, JAM-3 Protein, JAM-C Protein, Jcam3 Protein, JAM-2 Protein, JAMC Protein, junctional adhesion molecule 3 Protein, junctional adhesion molecule 3b Protein, junctional adhesion molecule 3a Protein, junction adhesion molecule 3 Protein, JAM3 Protein, jam3b Protein, jam3a Protein, Jam3 Protein

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].

Poids moléculaire: 36.5 kDa

NCBI Accession: NP_116190