JAM3 Protein (Ala149Pro) (Fc Tag,His tag)

N° du produit ABIN7534135

Détail du produit

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Type de proteíne: Recombinant

Attributs du protein: Ala149Pro

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette JAM3 protéine est marqué à la Fc Tag,His tag.

Fonction: Recombinant Human JAM-3(A149P) Protein

Séquence: VNLKSSNRTP VVQEFESVEL SCIITDSQTS DPRIEWKKIQ DEQTTYVFFD NKIQGDLAGR AEILGKTSLK IWNVTRRDSA LYRCEVVARN DRKEIDEIVI ELTVQVKPVT PVCRVPKPVP VGKMATLHCQ ESEGHPRPHY SWYRNDVPLP TDSRANPRFR NSSFHLNSET GTLVFTAVHK DDSGQYYCIA SNDAGSARCE EQEMEVYDLN

Specificité: Val32-Asn241(A149P)

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Autre désignation: JAM-3 (JAM3 Produits)

Synonymes: JAM3 Protein, jam3 Protein, sr:nyz155 Protein, wu:fb30h11 Protein, wu:fc08c06 Protein, wu:fc13e04 Protein, wu:fc25g11 Protein, jamc.2 Protein, 1110002N23Rik Protein, JAM-3 Protein, JAM-C Protein, Jcam3 Protein, JAM-2 Protein, JAMC Protein, junctional adhesion molecule 3 Protein, junctional adhesion molecule 3b Protein, junctional adhesion molecule 3a Protein, junction adhesion molecule 3 Protein, JAM3 Protein, jam3b Protein, jam3a Protein, Jam3 Protein

Sujet:

Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

Name: JAM3,JAM-2,JAM-3,JAM-C,JAMC

ID gène: 83700

UniProt: Q9BX67