LIN28B Protein (His tag)

N° du produit ABIN2724754

Détail du produit

Antigène: LIN28B (Lin-28 Homolog B (LIN28B))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LIN28B protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human LIN28B (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 20 mM PB, pH 7.4.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: LIN28B (Lin-28 Homolog B (LIN28B))

Autre désignation: Lin28b (LIN28B Produits)

Synonymes: csdd2 Protein, LIN-28 Protein, CSDD2 Protein, 2810403D23Rik Protein, D030047M17Rik Protein, Lin-28.2 Protein, lin-28 homolog B Protein, lin-28 homolog B S homeolog Protein, lin-28 homolog B (C. elegans) Protein, LIN28B Protein, lin28b Protein, lin28b.S Protein, Lin28b Protein

Sujet: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3&apos UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

Poids moléculaire: 26.9 kDa

NCBI Accession: NP_001004317