MAL Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725234

Détail du produit

Antigène: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant A

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MAL protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MAL (transcript variant a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Autre désignation: Mal (MAL Produits)

Synonymes: AI326936 Protein, Bp50 Protein, GP39 Protein, HIGM1 Protein, IGM Protein, IMD3 Protein, T-BAM Protein, TRAP Protein, Tnfrsf5 Protein, p50 Protein, Mpv17 Protein, Vip17 Protein, mal Protein, wyatt Protein, MALGENE Protein, im:7142606 Protein, zgc:112003 Protein, mal, T-cell differentiation protein Protein, CD40 antigen Protein, myelin and lymphocyte protein, T cell differentiation protein Protein, myelin and lymphocyte protein Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog Protein, MAL Protein, Cd40 Protein, Mal Protein, LOC100135389 Protein, mal Protein, tirap.L Protein

Sujet: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Poids moléculaire: 16.5 kDa

NCBI Accession: NP_002362

Pathways: Asymmetric Protein Localization