SPG21 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725535

Détail du produit

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SPG21 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Maspardin (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Autre désignation: Maspardin (SPG21 Produits)

Synonymes: ACP33 Protein, GL010 Protein, MAST Protein, BM-019 Protein, C78576 Protein, D9Wsu18e Protein, Maspardin Protein, wu:fd07h02 Protein, zgc:73091 Protein, SPG21, maspardin Protein, spastic paraplegia 21 (autosomal recessive, Mast syndrome) Protein, SPG21, maspardin S homeolog Protein, SPG21 Protein, Spg21 Protein, spg21.S Protein, spg21 Protein

Sujet: The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 34.8 kDa

NCBI Accession: NP_057714