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SPG21 Protein (AA 1-308) (His tag)

SPG21 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN666752
  • Antigène Voir toutes SPG21 Protéines
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-308
    Origine
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 6
    • 2
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SPG21 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    SPG21, 1-308 aa, Human, His-tagged, Recombinant, E.coli
    Pureté
    > 95 % by SDS - PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
    Stock
    4 °C
  • Antigène
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Autre désignation
    SPG21 (SPG21 Produits)
    Synonymes
    ACP33 Protein, GL010 Protein, MAST Protein, BM-019 Protein, C78576 Protein, D9Wsu18e Protein, Maspardin Protein, wu:fd07h02 Protein, zgc:73091 Protein, SPG21, maspardin Protein, spastic paraplegia 21 (autosomal recessive, Mast syndrome) Protein, SPG21, maspardin S homeolog Protein, SPG21 Protein, Spg21 Protein, spg21.S Protein, spg21 Protein
    Sujet
    Spastic paraplegia 21(SPG21), also known as Maspardin, binds to the hydrophobic C-terminal amino acids of CD4 and may play a role as a negative regulatory factor in CD4-depenent T-cell activation. This protein is widely expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Mutations in SPG21 cause Mast syndrome, an autosomal-recessive complicated form of hereditary spastic paraplegia characterized by dementia, thin corpus callosum and white matter abnormalities. Recombinant human SPG21 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: ACP33, BM-019, GL010, Maspardin, MAST, Spastic paraplegia 21 isoform a Acid cluster protein 33, BM019, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21. NCBI no.: NP_057714
    Poids moléculaire
    37.1 kDa (328aa), confirmed by MALDI-TOF.
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